Not everyone with type 1 or type 2 narcolepsy experiences the same symptoms. They have called for more research involving people presenting with type 2 narcolepsy to understand the classification better. The authors of the study suggest, therefore, that doctors may sometimes be confusing type 2 narcolepsy with other sleep disorders. For example, a 2018 study found that teenagers with a diagnosis of type 2 narcolepsy had symptoms that improved over time. Some experts argue that type 2 narcolepsy might be an incorrect term to use. In fact, the NORD states that the exact cause of type 2 narcolepsy is unknown. Its causes are also less clear to experts. It typically presents with similar symptoms to type 1 narcolepsy, but these symptoms may change over time. The prevalence of type 2 narcolepsy is uncertain because it is not as well-studied as type 1 and is harder to diagnose. However, more research is necessary to confirm these influencing factors. a sudden change in regular sleep patterns.the flu vaccine Pandemrix - a 2013 study found that between 1 in 57,500 and 1 in 52,000 people developed narcolepsy after having the vaccine during a swine flu epidemic in the United Kingdom.an infection, such as swine flu or a streptococcal infection.hormonal changes, such as those that occur in puberty or the menopause.Other possible causes of or triggers for type 1 or type 2 narcolepsy may include: Injury could be due to trauma, tumors, or brain disease. Injury to the brain: Although rare, injuries to the parts of the brain responsible for regulating sleep patterns could cause hypocretin levels to become low.Genetic history: Although narcolepsy is not a genetic condition, researchers believe that 1 in 10 people with the disorder have a close relative with the same symptoms.The National Organization for Rare Disorders (NORD) in the U.S states that there is increasing evidence to suggest that narcolepsy is an autoimmune disorder. The part of the brain responsible for producing hypocretin is the same part that makes TRIB2. Some studies have shown that people with narcolepsy produce antibodies that attack a protein called TRIB2. Autoimmune disorders: Autoimmune disorders occur when the body produces antibodies, which attack healthy cells and tissues.Hypocretin helps the brain regulate sleep cycles.Ĭertain factors can cause hypocretin levels to lower, triggering narcolepsy. Researchers believe that low levels of a naturally occurring hormone called hypocretin are the main cause of type 1 narcolepsy.
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